Treatments
Polynucleotides
You may not have heard of polynucleotides before; firstly, what is it? DNA is an example of a polynucleotide. Polynucleotides used in cosmetic medicine are made from highly purified fragments of DNA, extracted from trout or salmon sperm. These fragments of DNA are distilled into different strengths and suspended in sterile water ready for injection. The polynucleotides in Plinest, Plinest Eye, Newest and Plinest Hair are extracted from the same trout used in the food industry. Trout and salmon sperm DNA closely resembles human DNA.
Polynucleotides are used in aesthetic medicine to help improve dull skin, wrinkles, uneven pigmentation, redness, dark circles, acne scarring, stretchmarks, surgical scars and hair loss. It is a versatile treatment that can be used on skin anywhere on the body, not just the face and scalp.
Polynucleotides stimulate a receptor that sits on top of cells, which triggers the repair and production of new fibroblasts, which help to boost the skin’s structural framework. Polynucleotides boost collagen and elastin formation and increase hyaluronic acid production in the skin. They lead to the production of new micro-blood vessels which are able to provide more nutrients and oxygen to the surrounding tissues and improve wound healing and tissue repair. Polynucleotides are able to regulate the activity of melanocyte cells, which produce pigmentation and reduce inflammation within the skin. In terms of stimulating new hair growth, polynucleotides have been found to regenerate hair follicles and can be an excellent treatment for hair loss in females and males.
After numbing cream is applied to the skin and the skin is thoroughly cleaned, polynucleotides are injected into the superficial layer of the skin. Either a fine needle or a cannula is used to administer the treatment into the target area. A course of 3 – 4 treatments 3 weeks apart is recommended to achieve optimal results. The results are not instant but improvement can be noted from about 3 weeks and continues to improve over 3 months. Patients report a general improvement in the skin and report skin feels smoother and better hydrated. Fine lines and wrinkles appear softer, and acne scarring looks less pronounced. When treating hair loss in the crown of the head or near the hairline, new hair growth can be noted. It is important to note, however, that as with any injectable treatment, results will vary between individuals as the clinical response of the treatment will depend on biological factors and lifestyle factors. To help maintain results after the initial course, a one-off maintenance treatment is recommended every 6 months. If you choose not to maintain the results with further treatment, your skin will return to its pre-treatment state over time.
Book a ConsultationAt a glance
Treatment results
Improvement in skin laxity
Treatment time
Approx. 60 minutes
Anaesthesia
Topical numbing cream
Downtime
Minimal
Treatment frequency
After baseline course, 1 session every 6 months
Treatment
Frequently asked questions
Am I suitable for this treatment?
Dr Nandi will carry out a thorough consultation before suggesting the best treatment. Polynucleotides have been growing in popularity across clinics as more and more people hear of the benefits and great results people have obtained after treatment. It is great for adults of all ages who are concerned with fine lines, loss of tone, dryness, laxity, acne scars, stretch marks and sun damage.
Is this treatment safe?
The polynucleotides are highly purified and then sterilised from a licensed source, the production is regulated and the manufacturing process meets the required CE standards of safety. The science is evidence-based and there are multiple published scientific papers demonstrating safety and efficacy in using polynucleotides.
Is this treatment painful?
Dr Nandi will apply a topical numbing cream to the treatment area for around 25 minutes before the procedure, as injections can cause a bit of stinging.
Are there any side effects or risks?
Treatment with polynucleotides is a very safe, low-risk treatment. As with many injectable treatments, mild swelling, redness, and bruising are expected side effects. Swelling and redness usually settle within a day or so, and no significant downtime is experienced.
What downtime should I expect?
You may continue with most everyday activities, but there will likely be small bumps just under the skin that will be visible and may take around 24 hours to settle. You may also have a few bruises, some mild redness and swelling. Any bruising may be more apparent the next day and can take around 1 – 2 weeks to resolve.
Price
From £ 250
Testimonials
What our patients say...
The best recommendations for Rita! Rita is very professional and very friendly. I am always very excited when I am talking with Rita about my skincare routine. Many thanks for all your advices, help and for the best service on taking care of my skincare routine!
Gintare Rasymiene
Thank you. I am happy with your hospitality, attitude, care after the procedures and professional work on my face, I like the change, and everyone notices it. I am glad that I chose you, you are a professional. I highly recommend. Thanks Dr Rita
Ivan Donchev
Dr Rita Nandi is very professional and explains each step of the procedure, she takes time to reassure you if it is a first time having a filler treatment, and answers any questions you may have. She is a very patient doctor who takes time and looks after her clients before and after the procedure, unless other clinics! I had fillers on my cheekbones and my chin and the result is very natural and beautiful and it was not painful at all. I will definitely have another treatment soon with Dr Nandi for my jawline.
Kari G
I’m very glad to say that Dr Nandi delivered beyond my expectations. Not only does Dr Nandi have a friendly & kind personality, her knowledge is fantastic and cohesive, she thoroughly talked me through Bruxism, the implications and side effects, whilst taking the time to understand my journey with Bruxism. During the Botox procedure, Dr Nandi talked me thorough every step of the way to ensure I knew what was happening whilst allowing me to experience a pain free procedure. I find Dr Nandi’s attentiveness and naturally empathetic & caring approach towards her clients very nice and thoughtful to experience. All in all, I wholeheartedly recommend Dr Nandi.
Israt R Chow
I had my lips filled with Dr Nandi last month and honestly I couldn’t have hoped for a more amazing first filler experience. I’ve never had anything like this done before and I was extremely nervous, but Dr Rita made me feel unbelievably relaxed and taken care of. She saw to my every want and need and covered every base possible to ensure my health was first priority, and then the results of the procedure were incredible! I never knew my lips could look so good!! They look so natural no one even suspects I have filler, which is exactly what I wanted.
I look forward to seeing her again for every treatment of this type I have in the future. 10000% would recommend!!!
Haze
Treatments
Related Treatments
Treatment
Sunekos
Sunekos skin booster is a more natural injectable treatment consisting of a patented formula of amino acids and hyaluronic acid used for areas of the face and body to improve conditions.
View TreatmentTreatment
Profhilo
Profhilo is a multi-award-winning treatment consisting of one of the highest concentrations of hyaluronic acid on the market.
View TreatmentTreatment
Redensity 1
Redensity 1 is an award-winning, revolutionary injectable treatment that can boost the appearance of the skin on the face, decolletage and hands.
View TreatmentTreatment
Sunekos
Sunekos skin booster is a more natural injectable treatment consisting of a patented formula of amino acids and hyaluronic acid used for areas of the face and body to improve conditions.
View TreatmentTreatment
Profhilo
Profhilo is a multi-award-winning treatment consisting of one of the highest concentrations of hyaluronic acid on the market.
View TreatmentTreatment
Redensity 1
Redensity 1 is an award-winning, revolutionary injectable treatment that can boost the appearance of the skin on the face, decolletage and hands.
View Treatment